Endocrine Abstracts

Introduction: Gynecomastia is a benign excessive proliferation of glandular tissue in the male breast and results from an increased breast estrogen/androgen activity ratio. It may be physiological (infancy, puberty or aging) or pathological. The most common cause is drug-induced. Although hyperthyroidism is a rare cause(1.5%), gynecomastia occurs in up to 25-40% of males with Graves’ disease and is often undiagnosed. Its development as the first manifestation of this thyr...

Introduction: Several formulas are described to calculate the Insulin Dose to start insulin pump therapy. However, there are no data demonstrating their effectiveness in achieving good glycemic control.Aim: To assess the Total Daily Dose of Insulin (TDDI) at 3 months after beginning an insulin pump, and determine which formula most closely matches the TDDI required in cases where good glycemic control is achieved after that period....

Introduction: Caloric restriction combined with overtraining can result in a total body energy deficit, which in turn is associated with multiple deleterious endocrine consequences, including hypogonadotropic hypogonadism. This can be a reversible cause of primary infertility, but its occurrence in men is still poorly recognized.Case Report: We report a case of a 39-year-old male evaluated in an urology appointment for primary infertility. He had a histo...

Introduction: Fine needle aspiration cytology(FNAC) is the mainstay for evaluation of nodular thyroid disease. Internationally reported prevalence for Bethesda I(unsatisfactory sample) category is 5-60%. Several factors may determine this result, including patient and nodules’ features as well as both FNAC performer and pathologists’ skills. Few studies have evaluated pre-procedure factors associated with unsatisfactory cytology results. If present, recognizing these...

Background: In 15% of prolactinomas there is dopamine agonist(DA) resistance. The clinical characteristics, the best diagnostic and therapeutic management of these cases have not been established so far.Aim: To characterize patients taking a high dose cabergoline(≥ 3mg/week) and then describe clinical, biochemical and imaging features of cabergoline-resistant cases.Methods: Retrospective study with 5 centers representing the ...

IntroductionKetosis-Prone Diabetes (KPD) is a heterogeneous condition that shares clinical characteristics of type 1 and type 2 diabetes. It is usually a challenging diagnosis because patients are prone to develop diabetic ketoacidosis (DKA) without having the classic clinical phenotype of autoimmune type 1 diabetes.Case reportA Caucasian 26-years-old female with known history of renal transplant, morbid obes...

Introduction: Hyperglycaemia has been associated with worse maternal and foetal outcomes as well as higher risk for future type 2 diabetes (T2D).Objectives: We study the association between glucose above diagnostic threshold (GADT) at gestational diabetes (GD) diagnosis and risk of perinatal complications and maternal glucose abnormalities at post-partum.Materials and Methods: Retrospective study based on the national register of G...